First successful treatment of pediatric cerebral palsy with autologous cord blood: Awoken from a persistent vegetative state

First successful treatment of pediatric cerebral palsy with autologous cord blood: Awoken from a persistent vegetative state

May 23, 2013 — Bochum's medics have succeeded in treating cerebral palsy with autologous cord blood. Following a cardiac arrest with severe brain damage, a 2.5 year old boy had been in a persistent vegetative state -- with minimal chances of survival. Just two months after treatment with the cord blood containing stem cells, the symptoms improved significantly; over the following months, the child learned to speak simple sentences and to move.

"Our findings, along with those from a Korean study, dispel the long-held doubts about the effectiveness of the new therapy," says Dr. Arne Jensen of the Campus Clinic Gynaecology. Together with his colleague Prof. Dr. Eckard Hamelmann of the Department of Paediatrics at the Catholic Hospital Bochum (University Clinic of the RUB), he reports in the journal Case Reports in Transplantation.

The parents searched the literature for treatment options

At the end of November 2008, the child suffered from cardiac arrest with severe brain damage and was subsequently in a persistent vegetative state with his body paralysed. Up to now, there has been no treatment for the cause of what is known as infantile cerebral palsy. "In their desperate situation, the parents searched the literature for alternative therapies," Arne Jensen explains. "They contacted us and asked about the possibilities of using their son's cord blood, frozen at his birth."

"Threatening, if not hopeless prognosis"

Nine weeks after the brain damage, on 27 January 2009, the doctors administered the prepared blood intravenously. They studied the progress of recovery at 2, 5, 12, 24, 30, and 40 months after the insult. Usually, the chances of survival after such a severe brain damage and more than 25 minutes duration of resuscitation are six per cent. Months after the severe brain damage, the surviving children usually only exhibit minimal signs of consciousness. "The prognosis for the little patient was threatening if not hopeless," the Bochum medics say.

Rapid recovery after cord blood therapy

After the cord blood therapy, the patient, however, recovered relatively quickly. Within two months, the spasticity decreased significantly. He was able to see, sit, smile, and to speak simple words again. Forty months after treatment, the child was able to eat independently, walk with assistance, and form four-word sentences. "Of course, on the basis of these results, we cannot clearly say what the cause of the recovery is," Jensen says. "It is, however, very difficult to explain these remarkable effects by purely symptomatic treatment during active rehabilitation."

In animal studies, stem cells migrate to damaged brain tissue

In animal studies, scientists have been researching the therapeutic potential of cord blood for some time. In a previous study with rats, RUB researchers revealed that cord blood cells migrate to the damaged area of ​​the brain in large numbers within 24 hours of administration. In March 2013, in a controlled study of one hundred children, Korean doctors reported for the first time that they had successfully treated cerebral palsy with allogeneic cord blood.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

Electronic Components distributor:http://www.suvsystem.com

Connectors Distributor:http://www.suvsystem.com/l/Connectors-1.html

IC Distributor:http://www.suvsystem.com/l/IC(Integrated-Circuits)-1.html

LED Distributor:http://www.suvsystem.com/l/LED-1.html

Capacitor Distributor:http://www.suvsystem.com/l/Capacitor-1.html

Transistor Distributor:http://www.suvsystem.com/l/Transistors-1.html

Resistor Distributor:http://www.suvsystem.com/l/Resistors-1.html

Diode Distributor:http://www.suvsystem.com/l/Diodes-1.html

SUV System Ltd insists on the managing faith ofsincereness,speciality,foresight, win-win,so we build up stable-relationship customers located all over the world, including the States, Europe, Argentina, UAE, Malaysia, Australia,and India etc

we are focus on the following fields,and hope we can help you.

CRGV0603F549K CRGV0603F536K CRGV0603F523K CRGV0603F511K CRGV0603F499K CRGV0603F487K CRGV0603F475K CRGV0603F464K CRGV0603F453K CRGV0603F442K CRGV0603F432K CRGV0603F422K CRGV0603F412K CRGV0603F402K CRGV0603F392K CRGV0603F383K CRGV0603J560K CRGV0603J510K CRGV0603J4M7 CRGV0603J4M3 CRGV0603J470K CRGV0603J430K CRGV0603J3M9 CRGV0603J3M6 CRGV0603J3M3 CRGV0603J3M0 CRGV0603J390K CRGV0603J360K CRGV0603J330K CRGV0603J300K CRGV0603J2M7 CRGV0603J2M4 CRGV0603J2M2 CRGV0603J2M0 CRGV0603J270K CRGV0603J240K CRGV0603J220K CRGV0603J200K CRGV0603J1M8 CRGV0603J1M6
http://www.suvsystem.com/a/1472.aspx