Why smokers gain weight when they quit smoking: Changes in intestinal flora

Why smokers gain weight when they quit smoking: Changes in intestinal flora

Aug. 29, 2013 — Most smokers put on a couple of kilos when they quit smoking. This is not due to an increased calorie intake, but to a change in the composition of the intestinal flora after quitting smoking, as a study supported by the Swiss National Science Foundation (SNSF) suggests.

---

Share This:

When smokers wave goodbye to their cigarettes, eighty per cent of them put on seven kilos on average. Their weight increases even if their calorie intake remains the same or even falls compared to the level before quitting smoking. What is the reason for this weight gain?

Researchers working with Gerhard Rogler of Zurich University Hospital attribute the cause to a changed composition of the bacterial diversity in the intestine. As they recently showed in a study in PLoS One, the bacterial strains that also prevail in the intestinal flora of obese persons take the upper hand in people giving up smoking.

Comparison of stool samples

Rogler and his colleagues of the Swiss IBD cohort study examined the genetic material of intestinal bacteria found in the faeces and studied stool samples which they had received from twenty different persons over a period of nine weeks -- four samples per person. The test persons included five non-smokers, five smokers and ten persons who had quit smoking one week after the start of the study.

While the bacterial diversity in the faeces of smokers and non-smokers changed only little over time, giving up smoking resulted in the biggest shift in the composition of the microbial inhabitants of the intestines. The Proteobacteria and Bacteroidetes fractions increased at the expense of representatives of the Firmicutes and Actinobacteria phyla. At the same time, the test subjects who had quit smoking gained an average of 2.2 kilos in weight although their eating and drinking habits remained the same (with the exception that, towards the end of the study, they drank on average a little more alcohol than before quitting smoking).

More efficient utilisation

Their results reflected those seen in previous studies conducted with mice, says Rogler. When other scientists transplanted the faeces of obese mice into the intestines of normal-weight mice some years ago, they saw that both the fractions of the Proteobacteria and Bacteroidetes in the gut flora as well as the weight of the mice treated increased. The new gut flora apparently used the energy contained in the nutrition more efficiently.

Rogler and his colleagues assume that the same effect also manifests itself in their test subjects. The composition of the diverse bacteria in the intestinal flora, which changes after giving up smoking, probably provides the body with more energy, resulting in new non-smokers gaining weight.

Swiss IBD cohort study

With the aim of gaining a better understanding of inflammatory bow-el diseases or IBD, specialist hospitals, private practice physicians and university institutions have come together to pool their knowledge. They are collecting the medical data of now nearly 2,000 affected persons who are participating in this long-term study.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

Electronic Components distributor:http://www.suvsystem.com

Connectors Distributor:http://www.suvsystem.com/l/Connectors-1.html

IC Distributor:http://www.suvsystem.com/l/IC(Integrated-Circuits)-1.html

LED Distributor:http://www.suvsystem.com/l/LED-1.html

Capacitor Distributor:http://www.suvsystem.com/l/Capacitor-1.html

Transistor Distributor:http://www.suvsystem.com/l/Transistors-1.html

Resistor Distributor:http://www.suvsystem.com/l/Resistors-1.html

Diode Distributor:http://www.suvsystem.com/l/Diodes-1.html

SUV System Ltd insists on the managing faith ofsincereness,speciality,foresight, win-win,so we build up stable-relationship customers located all over the world, including the States, Europe, Argentina, UAE, Malaysia, Australia,and India etc

we are focus on the following fields,and hope we can help you.

Connectors IR transistor PANASONIC Resistors chip Filter saws AVX Resistors Other Parts ON Diodes ALTERA IC Cypress IC Renesas parts IC Fairchild Semiconductor Transistors Diodes Inc HARRIS IC Resistors Chip Fuses NXP Transistors ROHM Resistors LED MURATA IC IC(Integrated Circuits) Resistor Arrays Transistors Freescale Chip Inductors About US Metal Can Packages Transistors Zener Diodes Military IC BB IC LITTELFUSE Diodes Switching Diodes Current Sensors Resistors ST Transistors Transistors Atmel IC VISHAY IC ON Transistors Texas Instruments(TI) IC Diodes ELPIDA IC NEC Diodes
http://www.suvsystem.com/a/5366.aspx